Heart mitral valve disease (MVD) is a terminal illness which may afflict over half of all cavalier King Charles spaniels by the age of 5 years and nearly all Cavaliers by age 10 years. It is CKCSs' leading cause of death.
- More: Cavalier King Charles spaniel MVD
- Mitral valve disease breeding protocol
- A few words about pimobendan (Vetmedin)
- ACVIM cardiologists consensus statement
- Research news
- USA researchers find a new therapy which restores light sensitivity to retina of dogs blinded by retinal atrophy.
- New drug lets paralyzed rats move after spinal cord injuries.
- UK researchers find asymptomatic cavaliers with a syrinx appear more likely to display clinical signs later in life than those without.
- Belgian researchers find no significant difference between CT scans and MRI scans detecting Chiari-like malformation in cavaliers.
- UK Prof. Corcoran reports to UK's cavalier club on current mitral valve disease research.
- Infrared imaging study finds 90% success in identifying dogs with Type I intervertebral disk disease.
- Colin Driver joins the UK's Canine Chiari and Syringomyelia Research Group.
- Ceva's troubling medical treatment study of unsuspecting MVD-affected dogs in heart failure.
- Tufts University's vet school seeks healthy CKCSs for muscle mass clinical trial.
- UK surgeons report limited success inserting tracheal stents for temporary tracheostomies in three brachycephalic cavaliers.
- UK researchers find oral phenobarbital, imepitoin, potassium bromide, and levetiracetam likely are effective to treat idiopathic epilepsy, with a big BUT.
- OUR BLOG: Just Asking: What’s up with Vetmedin’s ‘EPIC Trial’?
- Japanese veterinary heart surgeon summarizes current methods of canine mitral valve repairs.
- Syringomyelia in South African cavaliers is 41%.
- Veterinary cardiologist Mark Kittleson dumps on EPIC Trial -- says it has a 50-50 chance.
- Japanese researchers find left atrial enlargement and function correlate with prognosis of early death of MVD dogs.
- Three definitions of Chiari-like malformation are compared in asymptomatic non-CKCS dogs.
- OUR BLOG: So your cavalier has a heart murmur. What do you do next?
- SM study of all cavaliers registered in Denmark in 2001 shows 15.4% have SM symptoms after age 6 years.
- OUR BLOG: Do MVD-affected cavalier King Charles spaniels really need taurine supplements?
- Joe Wakshlag is making some progress in his education about feeding dogs what they need.
- Benazepril does not prevent furosemide-induced RAAS activation, in a study of 10 healthy hounds.
- Penn Vet School's "I'm-Yunity" doses appear to be succeeding in treating hemangiosarcoma cancer.
- Only 60% of tested commercial pet foods correctly identify meat ingredients. Pork is the most frequent hidden ingredient.
- NEW WEBPAGE: Chronic ulcerative paradental stomatitis (CUPS) and the CKCS.
- NEW WEBPAGE: Degenerative myelopathy and the cavalier King Charles spaniel.
- International study confirms the obvious: the louder the murmur, the worse the MVD.
- NEW WEBPAGE: Miscellaneous, for those other cavalier disorders you keep asking about!
- Survey of 2,000+ breeders shows half (wisely) do not trust veterinarians for nutrition advice.
- UK vets find follicular cystititis in a cavalier.
- Serotonin study shows concentration highest in cavaliers, with or without mitral valve disease.
- Study of 84 American Brussels Griffons finds syringomyelia and Chiari-like malformation to be prevalent.
- North Carolina State veterinarians make progress in stem cell therapy for damaged heart tissue.
- International team of cardiologists find cavaliers have higher serotonin concentrations in platelets.
- Thailand researchers find no difference in serotonin concentrations between healthy dogs and those with MVD, but ...
- UK researchers find two aspects of cavalier skull conformation are associated with the development of SM.
- Swedish researchers find high blood NT-proANP concentrations can predict onset of congestive heart failure within months.
- UK's Dr. Jacques Penderis finds MRI noise results in some hearing loss in dogs.
- UK's Royal Veterinary College seeks CKCSs for neuropathic pain assessment study.
- OUR BLOG: When NOT to start giving your cavalier pimobendan (Vetmedin).
Veterinary specialists have designed breeding guidelines to eliminate early-onset mitral valve disease in cavalier King Charles spaniels.
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Syringomyelia (SM) is reported to be "very widespread" in the cavalier King Charles spaniel breed. Syringomyelia is a disorder of the brain and spinal cord, which may cause severe head and neck pain and possible paralysis.
- More: CKCS syringomyelia
- SM breeding protocol
- "Pedigree Dogs Exposed"
- "Pedigree Dogs Exposed - Three Years On"
- Estimated Breeding Values (EBVs)
- Research news
- Reduced rate MRI clinic locations
- MRI screening protocol for SM
Hip dysplasia reportedly afflicts up to one out of every four cavalier King Charles spaniels. It is a genetic disease which can cause the dogs pain and debilitation.
Low blood platelet counts in cavaliers usually are not a health problem. Many veterinarians are misled by low platelet counts to wrongly diagnose anemia or other serious disorders.
The size and shape of its head can cause serious breathing problems for the cavalier King Charles spaniel. Elongated soft palates, stenotic nares, everted laryngeal saccules, and laryngeal collapse are inherited developmental defects in the breed.
Cavalier King Charles spaniels appear predisposed to develop cerebellar infarcts, or strokes.
Cavaliers are predisposed to a form of congenital deafness, which is present at birth, and also to a progressive hereditary hearing loss, which usually begins during puppyhood and worsens, or progresses, until the dog is completely deaf, usually between the ages of three and five years.
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