Heart mitral valve disease (MVD) is a terminal illness which may afflict over half of all cavalier King Charles spaniels by the age of 5 years and nearly all Cavaliers by age 10 years. It is CKCSs' leading cause of death.
- More: Cavalier King Charles spaniel MVD
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- Find a cardiologist in the USA and Canada
- US cardiologists find mitral valve measurements are larger for dogs with advanced MVD.
- US researchers find associations between lesions at the atlantoaxial junction and SM in cavaliers.
- ACVIM cardiologists downplay the need for echocardiograms of cavaliers with newly discovered heart murmurs.
- NC State vet school needs cavaliers with Chiari-like malformation for pain studies.
- Dutch researcher examines MRIs and reports of 848 cavaliers and finds no significant relationship between clinical signs and CM/SM grade.
- Canadian researchers find that the timing of x-rays during breathing patterns can affect the vertebral heart score.
- US neurologists find association between medullary elevation and signs of SM, and that brainstem position relates to SM in CKCSs.
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- VetCompass analysis shows frequent diagnoses of dry eye in cavaliers.
- VetCompass analysis shows frequent diagnoses of cataracts in cavaliers.
- UK review of veterinary records of 1,875 cavaliers shows UK Kennel Club dogs had significantly low MVD diagnoses.
- More VetCompass analysis shows low diagnoses of CM and SM in cavaliers.
- OUR BLOG: “Purebred breeding” is a euphemism for accelerated genetic entrophy.
- VetCompass records from 2009-2014 show 37 out of 3,860 CKCSs were diagnosed by MRI to have CM/SM.
- UK research finds no correlation between barometric pressure changes and comfort levels of cavaliers with CM/SM.
- UK review of 111,967 dogs' veterinary records confirms that the cavalier ranks highest in MVD cases.
- Dutch research finds myringotomies are more successful than tympanostomies in slowing recurrences of PSOM.
- Penn Vet seeks cavaliers for new drug test.
- Dr. Meg Sleeper moves from Penn Vet to University of Florida.
- UK researchers develop a clinical severity score (CSS) to predict MVD severity and outcome.
- Researchers determine that moderate to severe pulmonary hypertension worsens outcome of dogs with MVD.
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- University of Georgia researchers compare ACE-inhibitors with aldosterone receptor blockers to combat aldosterone breakthrough in MVD-affected dogs.
- Researchers find gene expression of 5-HT2BR is higher in MVD-affected dogs.
- OUR BLOG: Is it 'Back to the Future' for the American Kennel Club?
- Japanese research shows pimobendan causes sudden death in end-stage heart failure in mice.
- Mississippi State University surgeons report long-term success of Chiari-like malformation surgeries.
- Flanders, Belgium now requires CM/SM and MVD testing of cavalier breeding stock.
- Scottish researchers identify 591 differentially expressed genes related to MVD in cavaliers.
- Pet MRI & Imaging Services, Purcellville, VA, offers CM/SM mini-scans for $525.00.
- Dr. George Strain finds tympanometry can be recorded in conscious dogs to assist in the evaluation of the middle ear conditions.
- NC State researchers find adding phenobarbital and bromide increases Levetiracetam's movement through epileptic dogs.
- Ukrainian researchers opine that the small dog genes IGF1 and/or STC2 relate to MVD in cavaliers.
- Swedish study finds serotonin levels increase in spayed bitches.
- German cardiologist examines serum MicroRNAs as diagnostic markers for mitral valve disease.
- OUR BLOG: All that cavalier owners need to know about the “Reverse Sneeze” or “Cavalier Snort”.
- UK's Royal Veterinary College's research team finds levetiracetam to effectively reduce epileptic seizures.
- Dr. Penny Watson discusses the "serotonin connection" between pancreatitis, mitral valve disease, syringomyelia, and other CKCS disorders.
- Korean researchers find link between advanced MVD and pancreatitis.
- "Pancreatitis in Cavaliers: What is it and what can I do about it?" DVD by Dr. Penny Watson.
- UK's Royal Veterinary College's new Epilepsy & Stress study needs affected dogs.
- Idexx Labs announces new early test -- SDMA -- for chronic kidney disease.
- Which disorder causes the other? Diabetes mellitus or exocrine pancreatic inflammation?
- Infiniti Medical reports successful results of 6-month trial of its Mitrex mitral valve implant device.
- Research shows limited genetic divergence between dog breeds in UK and South Africa.
- Echocardiographic measures of mitral regurgitation severity and mitral valve pathology enable researchers to reliably predict mortality.
- Scandinavian cardiologists find that increased left heart size can predict the risk of congestive heart failure in CKCSs.
Veterinary specialists have designed breeding guidelines to eliminate early-onset mitral valve disease in cavalier King Charles spaniels.
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Syringomyelia (SM) is reported to be "very widespread" in the cavalier King Charles spaniel breed. Syringomyelia is a disorder of the brain and spinal cord, which may cause severe head and neck pain and possible paralysis.
- More: CKCS syringomyelia
- SM breeding protocol
- Research news
- Reduced rate MRI clinic locations
- MRI screening protocol for SM
- Find a neurologist in the USA and Canada
- Estimated Breeding Values (EBVs)
- "Pedigree Dogs Exposed"
- "Pedigree Dogs Exposed - Three Years On"
Hip dysplasia reportedly afflicts up to one out of every four cavalier King Charles spaniels. It is a genetic disease which can cause the dogs pain and debilitation.
Low blood platelet counts in cavaliers usually are not a health problem. Many veterinarians are misled by low platelet counts to wrongly diagnose anemia or other serious disorders.
The size and shape of its head can cause serious breathing problems for the cavalier King Charles spaniel. Elongated soft palates, stenotic nares, everted laryngeal saccules, and laryngeal collapse are inherited developmental defects in the breed.
Cavalier King Charles spaniels appear predisposed to develop cerebellar infarcts, or strokes.
Cavaliers are predisposed to a form of congenital deafness, which is present at birth, and also to a progressive hereditary hearing loss, which usually begins during puppyhood and worsens, or progresses, until the dog is completely deaf, usually between the ages of three and five years.
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