Heart mitral valve disease (MVD) is a terminal illness which may afflict over half of all cavalier King Charles spaniels by the age of 5 years and nearly all Cavaliers by age 10 years. It is CKCSs' leading cause of death.
- More: Cavalier King Charles spaniel MVD
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- May 2015 - Researchers do not find a relationship between serotonin in blood platelets and development of MVD in cavaliers.
- May 2015 - US cardiologists find mitral valve measurements are larger for dogs with advanced MVD.
- May 2015 - US researchers find associations between lesions at the atlantoaxial junction and SM in cavaliers.
- May 2015 - ACVIM cardiologists downplay the need for echocardiograms of cavaliers with newly discovered heart murmurs.
- May 2015 - NC State vet school needs cavaliers with Chiari-like malformation for pain studies.
- May 2015 - Dutch researcher examines MRIs and reports of 848 cavaliers and finds no significant relationship between clinical signs and CM/SM grade.
- May 2015 - Canadian researchers find that the timing of x-rays during breathing patterns can affect the vertebral heart score.
- Apr 2015 - US neurologists find association between medullary elevation and signs of SM, and that brainstem position relates to SM in CKCSs.
- Apr 2015 - OUR BLOG: The CKCSC,USA makes part of its ethics code optional.
- Apr 2015 - VetCompass analysis shows frequent diagnoses of dry eye in cavaliers.
- Apr 2015 - VetCompass analysis shows frequent diagnoses of cataracts in cavaliers.
- Apr 2015 - UK review of veterinary records of 1,875 cavaliers shows UK Kennel Club dogs had significantly low MVD diagnoses.
- Apr 2015 - More VetCompass analysis shows low diagnoses of CM and SM in cavaliers.
- Apr 2015 - OUR BLOG: “Purebred breeding” is a euphemism for accelerated genetic entrophy.
- Apr 2015 - VetCompass records from 2009-2014 show 37 out of 3,860 CKCSs were diagnosed by MRI to have CM/SM.
- Apr 2015 - UK research finds no correlation between barometric pressure changes and comfort levels of cavaliers with CM/SM.
- APR 2015 - UK review of 111,967 dogs' veterinary records confirms that the cavalier ranks highest in MVD cases.
- Apr 2015 - Dutch research finds myringotomies are more successful than tympanostomies in slowing recurrences of PSOM.
- Apr 2015 - Penn Vet seeks cavaliers for new drug test.
- Mar 2015 - Dr. Meg Sleeper moves from Penn Vet to University of Florida.
- Mar 2015 - UK researchers develop a clinical severity score (CSS) to predict MVD severity and outcome.
- Mar 2015 - Researchers determine that moderate to severe pulmonary hypertension worsens outcome of dogs with MVD.
- Mar 2015 - OUR BLOG: The EPIC trial ends on schedule, but could a whitewash be in the works?
- Mar 2015 - University of Georgia researchers compare ACE-inhibitors with aldosterone receptor blockers to combat aldosterone breakthrough in MVD-affected dogs.
- Mar 2015 - Researchers find gene expression of 5-HT2BR is higher in MVD-affected dogs.
- Mar 2015 - OUR BLOG: Is it 'Back to the Future' for the American Kennel Club?
- Mar 2015 - Japanese research shows pimobendan causes sudden death in end-stage heart failure in mice.
- Mar 2015 - Mississippi State University surgeons report long-term success of Chiari-like malformation surgeries.
- Mar 2015 - Flanders, Belgium now requires CM/SM and MVD testing of cavalier breeding stock.
- Mar 2015 - Scottish researchers identify 591 differentially expressed genes related to MVD in cavaliers.
- Feb 2015 - Pet MRI & Imaging Services, Purcellville, VA, offers CM/SM mini-scans for $525.00.
- Feb 2015 - Dr. George Strain finds tympanometry can be recorded in conscious dogs to assist in the evaluation of the middle ear conditions.
- Feb 2015 - NC State researchers find adding phenobarbital and bromide increases Levetiracetam's movement through epileptic dogs.
- Feb 2015 - Ukrainian researchers opine that the small dog genes IGF1 and/or STC2 relate to MVD in cavaliers.
- Feb 2015 - Swedish study finds serotonin levels increase in spayed bitches.
- Feb 2015 - German cardiologist examines serum MicroRNAs as diagnostic markers for mitral valve disease.
- Feb 2015 - OUR BLOG: All that cavalier owners need to know about the “Reverse Sneeze” or “Cavalier Snort”.
- Feb 2015 - UK's Royal Veterinary College's research team finds levetiracetam to effectively reduce epileptic seizures.
- Jan 2015 - Dr. Penny Watson discusses the "serotonin connection" between pancreatitis, mitral valve disease, syringomyelia, and other CKCS disorders.
- Jan 2015 - Korean researchers find link between advanced MVD and pancreatitis.
- Jan 2015 - "Pancreatitis in Cavaliers: What is it and what can I do about it?" DVD by Dr. Penny Watson.
- Jan 2015 - UK's Royal Veterinary College's new Epilepsy & Stress study needs affected dogs.
- Jan 2015 - Idexx Labs announces new early test -- SDMA -- for chronic kidney disease.
Veterinary specialists have designed breeding guidelines to eliminate early-onset mitral valve disease in cavalier King Charles spaniels.
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Syringomyelia (SM) is reported to be "very widespread" in the cavalier King Charles spaniel breed. Syringomyelia is a disorder of the brain and spinal cord, which may cause severe head and neck pain and possible paralysis.
- More: CKCS syringomyelia
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- Find a neurologist in the USA and Canada
- Estimated Breeding Values (EBVs)
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Hip dysplasia reportedly afflicts up to one out of every four cavalier King Charles spaniels. It is a genetic disease which can cause the dogs pain and debilitation.
Low blood platelet counts in cavaliers usually are not a health problem. Many veterinarians are misled by low platelet counts to wrongly diagnose anemia or other serious disorders.
The size and shape of its head can cause serious breathing problems for the cavalier King Charles spaniel. Elongated soft palates, stenotic nares, everted laryngeal saccules, and laryngeal collapse are inherited developmental defects in the breed.
Cavalier King Charles spaniels appear predisposed to develop cerebellar infarcts, or strokes.
Cavaliers are predisposed to a form of congenital deafness, which is present at birth, and also to a progressive hereditary hearing loss, which usually begins during puppyhood and worsens, or progresses, until the dog is completely deaf, usually between the ages of three and five years.
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