Heart mitral valve disease (MVD) is a terminal illness which may afflict over half of all cavalier King Charles spaniels by the age of 5 years and nearly all Cavaliers by age 10 years. It is CKCSs' leading cause of death.
- More: Cavalier King Charles spaniel MVD
- Mitral valve disease breeding protocol
- A few words about pimobendan (Vetmedin)
- ACVIM cardiologists consensus statement
- Research news
- Find a cardiologist in the USA and Canada
- February 2017 -- USA researchers find promising CSF biomaker for early diagnosis of degenerative myelopathy.
- February 2017 -- Austrian heart clinic offers mitral valve repair surgery on MVD-affected dogs in heart failure.
- February 2017 -- Serum proteins are found to be differentially expressed in cavaliers with MVD.
- February 2017 -- OUR BLOG: Does detecting heart failure in MVD-affected cavaliers matter anymore?
- February 2017 -- Japanese researchers find left atrium strain can predict heart failure in MVD-affected dogs.
- January 2017 -- Nutri-Plus Gel stimulates the appetite of a cavalier in Stage C mitral valve disease suffering severe weight loss.
- January 2017 -- Italian researchers find cavaliers as the main represented breed for nuclear glycogen inclusions in the stomach's gastric glands.
- January 2017 -- Dr. Borgarelli seeks cavaliers in heart failure for minimally invasive mitral valve repair.
- January 2017 -- UK study identifies characteristics that cause painful Chiari-like malformation and syringomyelia in cavaliers.
- January 2017 -- UK study uses MRI scan measurements of hindbrain and craniocervical junction angles and distances to compare Chihuahuas, Affenpinschers and cavaliers with and without syringomyelia.
- January 2017 -- Phenobarbital and potassium bromide are effective supplements to imepitoin treatment of idiopathic epilepsy.
- January 2017 -- N-terminal BNP predictions of MVD status get more complicated.
- January 2017 -- OUR BLOG: All that cavalier owners need to know about spironolactone.
- January 2017 -- UK Kennel Club reports 2013-2014 compliance rate with its CM/SM breeding protocol was 0.28%.
- January 2017 -- UK researchers rate successful medications for Episodic Falling Syndrome in CKCSs.
- January 2017 -- UK study of 8,860 cavaliers shows that MVD Breeding Protocol works but breeders' compliance was poor.
- December 2016 -- Whole genome, next generation sequencing detects new muscular dystrophy mutation in a cavalier.
- December 2016 -- Study shows healthy cavaliers' mitral valve structure differs markedly from other breeds.
- December 2016 -- OUR BLOG: Why do any veterinarians prescribe useless drugs to MVD-affected cavaliers before heart failure?
- December 2016 -- Tufts' researchers test mesenchymal stem cell (MSC) treatments to improve MVD-affected dogs in heart failure.
- December 2016 -- NEW PAGE: Anesthesia and Sedatives in the Cavalier King Charles Spaniel.
- December 2016 -- UK study finds that cavaliers' cardiac-caused syncope collapses have increased troponin concentrations.
- December 2016 -- Polish researchers find four cell markers signal left atrium enlargement in MVD-dogs.
- December 2016 -- NEW PAGE: Patent Ductus Arteriosus (PDA) and the Cavalier King Charles Spaniel.
- November 2016 -- NEW TOPIC: Inflammatory bowel disease (IBD) in the cavalier King Charles spaniel.
- November 2016 -- NEW TOPIC: Glaucoma in the cavalier King Charles spaniel.
- November 2016 -- Cavalier eye sizes are large for small dogs but fit in the medium dog group.
- November 2016 -- UK Kennel Club approves MVD testing scheme for cavaliers.
- November 2016 -- Cavaliers were 15+% of dogs with erosive immune-mediated polyarthritis (IMPA).
- November 2016 -- Electronic von Frey aesthesiometer (eVF) testing fails to distinguish pain levels in 70 cavaliers.
- November 2016 -- French study of 1,668 cavalier bitches shows birth, still-born, and post natal mortality rates.
- November 2016 -- Cavaliers with ventriculomegaly may also have normal pressure hydrocephalus.
- November 2016 -- To feed or not to feed the pancreatitis patient? Who knows?
- November 2016 -- Simon Swift calls for parents/ grandparents of UK show cavaliers to meet MVD breeding protocol -- only 4% of CKCSs have been meeting that protocol.
- November 2016 -- UK and US researchers investigate links between epilepsy, drug-resistance, and affective disorders.
- November 2016 -- Pig bladder grafts successfully return sight to two cavaliers with corneal ulcers.
- November 2016 -- Brazilian researchers use digital video imaging to determine eye blink rates in cavaliers.
- November 2016 -- Belgian researchers recommend all cavaliers be tested for oversized platelets and mated accordingly.
- November 2016 -- 12.3% of Belgium cavaliers are estimated to be episodic falling syndrome carriers.
- October 2016 -- Thai cardiologists recommend "ECG monitoring should be performed in dogs chronically administered with pimobendan."
- October 2016 -- Tawian cardiologists find anemia increases with MVD progression and predicts mortality.
- October 2016 -- German study finds that video otoscopy beats ultrasound in diagnosing otitis media.
- October 2016 -- Korean researchers find cystatin-C (Cys-C) and symmetric dimethylarginine (SDMA) as useful biomarkers of MVD progression to heart failure.
- October 2016 -- NEW BOOK: "Cavalier King Charles Spaniel: Comprehensive Care from Puppy to Senior", by Charlotte Spencer.
- October 2016 -- OUR BLOG: Pimobendan's EPIC Study: The BAD and the UGLY!
- September 2016 -- OUR BLOG: So your cavalier has a heart murmur. What do you do next? UPDATED since the EPIC Study!
- September 2016 -- The EPIC Study concludes that pimobendan can prolong pre-heart failure by 15 months in MVD-affected dogs with echo and x-ray evidence of heart enlargement.
- September 2016 -- Pimobendan significantly prolonged survival time and reoccurrence of pulmonary edema in CHF dogs.
- September 2016 -- Acupuncture successfully controls pain symptoms in a CM/SM-affected cavalier.
- September 2016 -- Brazilian vets propose using the Cardiothoracic Ratio (CTR) to measure heart enlargement.
- September 2016 -- ACVIM issues "Consensus Recommendations on the Treatment and Prevention of Uroliths in Dogs".
- September 2016 -- University of Cincinnati's FETCH~LAB offers hearing tests for dogs.
- Septemer 2016 -- Brazilian study shows the jaw disorder, temporomandibular joint dysplasia, in cavaliers.
- September 2016 -- CSU vets aptly summarize using anesthesia on MVD-affected dogs.
- August 2016 -- NEW TOPIC: Check out our new discussion of shadow chasing cavaliers.
- August 2016 -- The EPIC Trial's final report on MVD-affected dogs is expected soon.
- August 2016 -- Southeast Veterinary Neurology offers reduced cost CM/SM screening for cavaliers.
- August 2016 -- Dr. Jerold Bell's new article, "Maintaining and Improving Breeds".
- August 2016 -- Cavaliers lead list of CM/SM-affected dogs treated in England primary-care clinics, 2009-2014.
- August 2016 -- OUR BLOG: Is the University of Washington’s “Rapamycin Intervention Trial in Pet Dogs” Unethical?
- August 2016 -- NEW PAGE: Xanthinuria in Cavalier King Charles Spaniels.
- August 2016 -- NEW TOPIC: Check out our new discussion of pregnancies and gestation periods.
- August 2016 -- NEW TOPIC: Check out our new discussion of keratitis -- inflammation of the cornea due to bacteria, fungus or virus.
- August 2016 -- Cavaliers were 10% of 5-year study of bilateral surgeries for patellar luxation.
- August 2016 -- OUR BLOG: Whither the EPIC Trial's final report? Something about it smells terribly funny.
Veterinary specialists have designed breeding guidelines to eliminate early-onset mitral valve disease in cavalier King Charles spaniels.
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Syringomyelia (SM) is reported to be "very widespread" in the cavalier King Charles spaniel breed. Syringomyelia is a disorder of the brain and spinal cord, which may cause severe head and neck pain and possible paralysis.
- More: CKCS syringomyelia
- SM breeding protocol
- Research news
- Reduced rate MRI clinic locations
- MRI screening protocol for SM
- Find a neurologist in the USA and Canada
- Use harnesses instead of leashes for CM/SM dogs
- Estimated Breeding Values (EBVs)
- "Pedigree Dogs Exposed"
- "Pedigree Dogs Exposed - Three Years On"
Hip dysplasia reportedly afflicts up to one out of every four cavalier King Charles spaniels. It is a genetic disease which can cause the dogs pain and debilitation.
Low blood platelet counts in cavaliers usually are not a health problem. Many veterinarians are misled by low platelet counts to wrongly diagnose anemia or other serious disorders.
The size and shape of its head can cause serious breathing problems for the cavalier King Charles spaniel. Elongated soft palates, stenotic nares, everted laryngeal saccules, and laryngeal collapse are inherited developmental defects in the breed.
Cavalier King Charles spaniels appear predisposed to develop cerebellar infarcts, or strokes.
Cavaliers are predisposed to a form of congenital deafness, which is present at birth, and also to a progressive hereditary hearing loss, which usually begins during puppyhood and worsens, or progresses, until the dog is completely deaf, usually between the ages of three and five years.
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- Cerebellar Infarcts -- Brain Strokes
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