Heart mitral valve disease (MVD) is a terminal illness which may afflict over half of all cavalier King Charles spaniels by the age of 5 years and nearly all Cavaliers by age 10 years. It is CKCSs' leading cause of death.
- More: Cavalier King Charles spaniel MVD
- Mitral valve disease breeding protocol
- A few words about pimobendan (Vetmedin)
- ACVIM cardiologists consensus statement
- Research news
- Find a cardiologist in the USA and Canada
- July 2015 - OUR BLOG: Heart failure in the MVD-affected cavalier King Charles spaniel.
- June 2015 - NEW WEBPAGE: Vestibular Disorders and the Cavalier King Charles Spaniel.
- June 2015 - US researchers study microRNAs as possible biomarkers of MVD progression.
- June 2015 - Cardiologist George Kramer competes for Wells Fargo prize for his Tucker valve to prevent backflow through heart valves.
- June 2015 - Danish kennel club continues the cavalier MVD breeding protocol through May 2017.
- June 2015 - US ophthalmologist warns that steroid treatment may worsen corneal dystrophy.
- June 2015 - Mitrex researchers report success and safety of its device with pigs.
- June 2015 - Out-crossing Griffon Bruxellois with Australian terrier reduced Chiari-like malformation and maintained breed standard in second generation.
- June 2015 - US veterinarians prove they remain useful tools of Hill's Pet Nutrition by endorsing it's junk food.
- June 2015 - NEW WEBPAGE: Corneal Ulcers and the Cavalier King Charles Spaniel.
- June 2015 - Researchers emphasize importance of differentiating urine crystals in cavaliers.
- June 2015 - Cardiologist Rebecca Stepien confirms "no proven benefit" to pimobendan at Stage B2 MVD.
- June 2015 - Cavalier displays tremors, facial twitches, and salivation syndromes due to pyrethrin poisoning from insecticides.
- May 2015 - Cavalier overcomes lymphocytic leukemia with stem cell from littermate.
- May 2015 - PennVet researchers reduce plasma NT-proBNP concentration in MVD-dogs in stable heart failure.
- May 2015 - Cardiologists compile echo findings in 126 older cavaliers.
- May 2015 - US researchers find pimobendan made no difference on incidence of arrhythmias of dogs in heart failure, compared to a placebo.
- May 2015 - Researchers do not find a relationship between serotonin in blood platelets and development of MVD in cavaliers.
- May 2015 - US cardiologists find mitral valve measurements are larger for dogs with advanced MVD.
- May 2015 - US researchers find associations between lesions at the atlantoaxial junction and SM in cavaliers.
- May 2015 - ACVIM cardiologists downplay the need for echocardiograms of cavaliers with newly discovered heart murmurs.
- May 2015 - NC State vet school needs cavaliers with Chiari-like malformation for pain studies.
- May 2015 - Dutch researcher examines MRIs and reports of 848 cavaliers and finds no significant relationship between clinical signs and CM/SM grade.
- May 2015 - Canadian researchers find that the timing of x-rays during breathing patterns can affect the vertebral heart score.
- Apr 2015 - US neurologists find association between medullary elevation and signs of SM, and that brainstem position relates to SM in CKCSs.
- Apr 2015 - OUR BLOG: The CKCSC,USA makes part of its ethics code optional.
- Apr 2015 - VetCompass analysis shows frequent diagnoses of dry eye in cavaliers.
- Apr 2015 - VetCompass analysis shows frequent diagnoses of cataracts in cavaliers.
- Apr 2015 - UK review of veterinary records of 1,875 cavaliers shows UK Kennel Club dogs had significantly low MVD diagnoses.
- Apr 2015 - More VetCompass analysis shows low diagnoses of CM and SM in cavaliers.
- Apr 2015 - OUR BLOG: “Purebred breeding” is a euphemism for accelerated genetic entrophy.
- Apr 2015 - VetCompass records from 2009-2014 show 37 out of 3,860 CKCSs were diagnosed by MRI to have CM/SM.
- Apr 2015 - UK research finds no correlation between barometric pressure changes and comfort levels of cavaliers with CM/SM.
- APR 2015 - UK review of 111,967 dogs' veterinary records confirms that the cavalier ranks highest in MVD cases.
- Apr 2015 - Dutch research finds myringotomies are more successful than tympanostomies in slowing recurrences of PSOM.
- Apr 2015 - Penn Vet seeks cavaliers for new drug test.
- Mar 2015 - Dr. Meg Sleeper moves from Penn Vet to University of Florida.
- Mar 2015 - UK researchers develop a clinical severity score (CSS) to predict MVD severity and outcome.
- Mar 2015 - Researchers determine that moderate to severe pulmonary hypertension worsens outcome of dogs with MVD.
- Mar 2015 - OUR BLOG: The EPIC trial ends on schedule, but could a whitewash be in the works?
- Mar 2015 - University of Georgia researchers compare ACE-inhibitors with aldosterone receptor blockers to combat aldosterone breakthrough in MVD-affected dogs.
- Mar 2015 - Researchers find gene expression of 5-HT2BR is higher in MVD-affected dogs.
- Mar 2015 - OUR BLOG: Is it 'Back to the Future' for the American Kennel Club?
Veterinary specialists have designed breeding guidelines to eliminate early-onset mitral valve disease in cavalier King Charles spaniels.
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Syringomyelia (SM) is reported to be "very widespread" in the cavalier King Charles spaniel breed. Syringomyelia is a disorder of the brain and spinal cord, which may cause severe head and neck pain and possible paralysis.
- More: CKCS syringomyelia
- SM breeding protocol
- Research news
- Reduced rate MRI clinic locations
- MRI screening protocol for SM
- Find a neurologist in the USA and Canada
- Estimated Breeding Values (EBVs)
- "Pedigree Dogs Exposed"
- "Pedigree Dogs Exposed - Three Years On"
Hip dysplasia reportedly afflicts up to one out of every four cavalier King Charles spaniels. It is a genetic disease which can cause the dogs pain and debilitation.
Low blood platelet counts in cavaliers usually are not a health problem. Many veterinarians are misled by low platelet counts to wrongly diagnose anemia or other serious disorders.
The size and shape of its head can cause serious breathing problems for the cavalier King Charles spaniel. Elongated soft palates, stenotic nares, everted laryngeal saccules, and laryngeal collapse are inherited developmental defects in the breed.
Cavalier King Charles spaniels appear predisposed to develop cerebellar infarcts, or strokes.
Cavaliers are predisposed to a form of congenital deafness, which is present at birth, and also to a progressive hereditary hearing loss, which usually begins during puppyhood and worsens, or progresses, until the dog is completely deaf, usually between the ages of three and five years.
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